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Capillary Flow in Micro-channels

Blood capillary is often studied because of its important role in clinical diagnosis. The blood sample must be introduced to an empty capillary micro-channel that guides the sample to an on-chip sensor for analyzing. Thus the filling characteristic of an empty micro-channel is an important aspect of study.

 

Computational analyses has been used for simulating of both Newtonian and non-Newtonian fluids in micro-channels and the results have been compared with theoretical analysis based on Washburn equation. The results of the simulations of water entering micro-channels with radius 25, 50, and 100 micron are shown in Figure 1, with the theoretical validation based on Washburn equation. Figure 2 shows the distance of blood penetration and withdrawal using the Carreau model for 25 micron, 50 micron and 100 micron capillaries. The penetration and withdrawal of blood in the capillary micro-channels can be observed. This research is being conducted in collaboration with the Department of ECECS (BioMEMS Lab).

 

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Figure 1 Simulation results for water in 25, 50, and 100 �m channels

 

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Figure 2 Results from simulation using Carreau model

 

 

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by zopeown last modified 2008-03-17 17:36